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Intriguingly, when older mice were given MOTS-c injections to restore their MOTS-c to more youthful levels, it reversed certain aging effects specifically, it restored insulin sensitivity in aged muscles and improved the animals exercise capacity to levels comparable with younger mice

Dev Biol 296(1):177189 Kalin RE et al (2007) Paracrine and autocrine mechanisms of apelin signaling govern embryonic and tumor angiogenesis

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Degradation of glutathione leads primarily to its constituent amino acids (e.g., cysteine, glycine), which can subsequently be used for glutathione synthesis inside the cell