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Dermoscopic appearance of a Spitz naevus in a male aged five years, showing a starburst pattern, indicating the radial growth phase of the tumour, central homogenous pigmentation surrounded by pseudopods and finger-like projections regularly and symmetrically distributed at periphery

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Notably, calcium bilirubinate may act as a nidus for agglomeration of cholesterol crystals and the development of cholesterol stones [19] (Fig

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Precision medicine approaches, which often use genomic and other biomarker information to target and tailor interventions, are precisely suited to addressing the challenge of heterogeneity