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The ability for patients to receive care from their own homes would largely disappear

Moreover, several studies suggest that 4-HNE can adduct with LKB1 to inhibit the activity of AMPK and further activate the mTOR pathway, resulting the disabled autophagy initiation [147, 162, 163]

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Based on the results of the short-term model, 20 g liraglutide was selected, and the potential benefit of liraglutide in OA-associated pain was assessed using the von Frey test (Fig