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Distribution of Cu Zn superoxide dismutase in rat liver
Minoxidil and finasteride are the most widely used approved treatments for androgenetic alopecia and work through established mechanisms: minoxidil extends the anagen phase primarily through potassium channel effects on follicle cells, while finasteride blocks the conversion of testosterone to DHT at the enzyme level
However, non-motor symptoms, such as cognitive impairment and autonomic dysfunction, potentially linked to neuroendocrine and metabolic dysfunction, are now widely recognized as important features that extend beyond the loss of dopaminergic neurons [1]
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