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Mechanistic Focus in Research Within experimental laboratory environments, FOXO4-DRI is often studied in relation to cellular signalling pathways associated with senescence and protein interaction dynamics

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In animal models, high-dose ketamine (100 mg/kg daily) caused mitochondrial swelling, DNA damage, and ATP production deficits (Huang et al., 2024)

2a, b), indicating that these interactions do not have a role in cell surface delivery

[DOI] [PMC free article] [PubMed] [Google Scholar] 66.Kaliman P., Alvarez-Lpez M.J., Cosn-Toms M., Rosenkranz M.A., Lutz A., Davidson R.J