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Melasma may also occur when starting or stopping hormonal contraception, including birth control pills, or with hormone replacement therapy

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While commercially available as the FDA-approved Ozempic and Wegovy, compounded semaglutide offers customized formulations and dosing adjustments through specialized pharmacies

[4] Both can cause similar side effects, such as nausea or digestive issues

Data from 8 randomized controlled trials (6,361 participants) indicated that this level of weight loss could last as long as 3.5 years, although information on long-term safety remains limited

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