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Contraindications include pregnancy or breastfeeding, active or suspected cancer, and severe liver or kidney disease

Many patients start with a 612 month commitment to reach their target weight, then transition to maintenance dosing to prevent regain

The study utilized flow cytometry for one hour

Another case-control study reported that individuals in the highest quintile of riboflavin status, as measured by red blood cell glutathione reductase activity, had approximately one-half the occurrence of age-related cataract as those in the lowest quintile of riboflavin status, though the results were not statistically significant (34)

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Higher-end formulations sometimes cite 4-5%, but irritation reports rise with concentration