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Among these, Helicobacter pylori infection is the most important since its prevalence has been estimated worldwide at 48%, despite wide regional discrepancies (Oceania 24% vs Africa 79%) ( Helicobacter pylori as cause of inflammatory gastritis in more of 90% of the cases has become clear ( Helicobacter pylori related gastritis initially involves the superficial layer of antrum mucosa of the stomach with an inflammatory mononuclear and plasma cells infiltrate

Reported effects in animal models include improved wound closure, modulation of inflammation, and support for cardiac and corneal tissue repair

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Continue metformin unchanged throughout the transition